0 = recently diagnosed

Range: 5.0-16%

DiRECT target: 15 kg

DiRECT range: 27-45

Range: 18-90 years

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Estimated Remission Probability
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Adjustment Factors
Likely Above 60%
Possible 30%-60%
Challenging Below 30%

This calculator is based on outcomes from the DiRECT trial (Diabetes Remission Clinical Trial), which found that ~86% of participants who lost 15+ kg within 6 years of diagnosis achieved remission. Adjustments are applied for individual factors:

Base: 86% (if <6 years, >=15 kg loss, A1c <=7%, age <=65, BMI <=35) Duration adj: -10% per year over 6 (max -50%) Weight loss adj: -15% per 5 kg below 15 kg target A1c adj: -5% per 0.5% above 7.0% (max -30%) Age adj: -10% if age >65 BMI adj: +5% if BMI >=35 (more fat mass to lose = more potential)

Remission is defined as HbA1c below 6.5% without glucose-lowering medications for at least 3 months. This calculator applies to type 2 diabetes only - it is not applicable to type 1 or LADA. Even a low probability does not mean remission is impossible - every individual's response differs.

! Medical Disclaimer
This calculator provides an educational estimate based on published DiRECT trial data. It is not a clinical prediction tool and does not account for all individual factors. Diabetes remission attempts should only be undertaken with close medical supervision. Do not stop medications without consulting your healthcare provider. This calculator applies to type 2 diabetes only.